Haematology disease areas
Haemophilia A
Haemophilia A is a rare, inherited bleeding disorder caused by deficient or defective factor VIII activity. It results in impaired coagulation, leading to prolonged bleeding, spontaneous haemorrhages, and joint damage.
Haemophilia B
Haemophilia B is a rare, inherited bleeding disorder caused by deficient or defective factor IX activity. It leads to impaired coagulation, resulting in prolonged bleeding, spontaneous haemorrhages, and joint damage.
Immune thrombocytopenia
Immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterised by immune-mediated platelet destruction and impaired platelet production, leading to thrombocytopenia and an increased risk of bleeding.
Paroxysmal nocturnal haemoglobinuria
Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, acquired clonal disorder of the haematopoietic stem cell characterised by complement-mediated intravascular haemolysis, anaemia and an increased risk of thrombosis.
Diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) is an aggressive form of non-Hodgkin lymphoma characterized by malignant proliferation of mature B-lymphocytes. It is the most common subtype of lymphoma, presenting with rapidly enlarging lymph nodes and systemic symptoms.
Myelofibrosis
Myelofibrosis is a rare myeloproliferative neoplasm characterized by progressive bone marrow fibrosis, leading to impaired haematopoiesis, cytopenias, and extramedullary blood cell production.